Jianing Jiang, Xiuhua Sun

Oncology Medicine Department, The Second Affiliated Hospital of Dalian Medical University

Objective:To make a research on the prognosis factors of non-hodgkin lymphoma (NHL) cases, and discuss how to improve the prognosis as far as possible. Method: To collect 200 cases of NHL in The Second Affiliated Hospital of Dalian Medical University from January 1st 2008 to January 1st 2013, except for the withdraw and the untreated, 172 cases were in the study with the follow-up visit information. To analyse the data by SPSS17.0 and compare the survival rate by Kaplan-Meier. To analyse the effects of different factors on the patients' prognosis. To use Cox model to analysis the single factor into multi-factor. Result: Except for the withdraw and the patients untreated, there were 172 cases in our rearch. The survival rate of 1 years, 3 years, 5 years is 72.7%, 50.6% and 36.0%. Analysed by single factor, the factors had an influence on the prognosis were age, Ann Arbor-Cotswolds, IPI, LDH, general syptom, pathological type and therapy scheme. There was no evidence confirming sex, frist zone, bone marrow puncture, extracapsular extension were the prognosis factors. Conclusion: 1.Age, Ann Arbor-Cotswolds, IPI, LDH, general syptom, pathological type and therapy scheme were related to the prognosis of NHL. Except for the last, all the factors were independent prognosis factors. 2. Our study hadn't testify gender, 1st zone, bone marrow puncture or involvement outside could affect the prognosis of NHL, so more researches needed to be done.

Key Words: Non-hodgkin lymphoma, Clinical features